Publications / Poster

A methylation state specific targeted background depletion technique for enrichment of ctDNA fraction

AACR Special Conference in Cancer Research: Liquid Biopsy

The study demonstrated a CRISPR/Cas12a technology that selectively removes unmethylated “non-cancer” DNA while preserving methylated “cancer” signals, enhancing detection accuracy. This multiplexable method improves the sensitivity of rare methylation event detection in both qPCR and sequencing assays.

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