THE SCIENCE
A biology-first view of cancer origins
Harbinger Health was founded on the belief that cancer is best understood at its earliest biological origins.
We do not view cancer as a static diagnosis, but as a process that begins and evolves long before clinical detection. By identifying the earliest biological signals of disease, we uncover trajectories that other approaches miss.
This perspective defines how we discover biomarkers, where resolution diagnostics fit within the patient journey, and how we create value, by intervening earlier, with prescription.
Pioneering the detection of early cancer.
Cancer is often treated as a binary condition; present or absent. Clinically, this distinction is necessary. Biologically, however, cancer emerges along a continuum.
It begins with subtle molecular changes that precede overt malignancy and evolves over time through interactions with normal tissue, immune responses, and developmental pathways.
Because this process is dynamic and heterogeneous, diagnostics are most informative when aligned to where an individual sits along this continuum.
Harbinger’s scientific approach is grounded in this understanding. We focus on defining a patient’s position along the cancer emergence spectrum and applying resolution diagnostics in a manner consistent with the underlying biology.
Clinical Evidence
Advancing insight through clinical research
Harbinger’s scientific platform is supported by a growing body of prospective clinical research. These studies generate the biological samples and clinical data needed to validate biomarkers, refine algorithms, and evaluate how resolution diagnostics can support clinical decision-making across the cancer care continuum.
